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Therefore, the overall effect of the KD on inflammation is influenced by local concentrations of ketone bodies in the affected tissues and the ratio of BHB to acetoacetate

The catalase enzyme (CAT) subsequently breaks down H 2 O 2 into H 2 O and O 2 , or it can be transformed by thiol peroxidases, such as glutathione peroxidase, which promote the reduction of H 2 O 2 and/or organic hydroperoxides into water and the corresponding alcohols

CB-Rs and the putative receptors are activated by eicosanoids such as N-arachidonoyl-ethanolamide (AEA) or anandamide , and 2-arachidonoyl-glicerol (2-AG), and by cannabinoids and their analogues

One or more interactions may be part of the proposed antioxidant mechanism of CCM, like neutralizing or scavenging free radicals, preventing oxidative cascades, quenching oxygen, inhibiting oxidative enzymes, and deactivating toxicants oxidative properties (Rao 1994

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doi: 10.1007/s00330-020-07240-7 28 ChoongC